Lipid content of human costal and articular cartilage.

Proteinpolysaccharides from human articular and costal cartilage.

Extra-cellular Lipid in the Matrix of Human Articular Cartilage.

The presence of fat and other lipids within the cytoplasm of cartilage cells has often been observed. Collins, Ghadially, and Meachim (1965) in a previous paper have described this phenomenon in some detail. They find that intra-cellular lipid is an almost constant feature of the chondrocytes of adult hyaline cartilage in various anatomical situations in man and rodents, that it is more promine...

The proteinpolysaccharides of human costal cartilage.

Water-soluble proteinpolysaccharides, called PPL, can be extracted from bovine nucleus pulposus in yields of 45%, and from bovine nasal cartilage in yields of 37% of the dry tissue weight. From human costal cartilage only 7% can be extracted. The method used to separate PPL from each of the first two tissues into four distinct fractions separates the PPL of human costal cartilage into four frac...

Topographical variation in glycosaminoglycan content in human articular cartilage.

The weight-bearing status of articular cartilage has been shown to affect its biochemical composition. We have investigated the topographical variation of sulphated glycosaminoglycan (GAG) relative to the DNA content of the chondrocyte in human distal femoral articular cartilage. Paired specimens of distal femoral articular cartilage, from weight-bearing and non-weight-bearing regions, were obt...

Differential Immunohistochemical Expression Pattern of Galectin-3 in Normal and Osteoarthritic Human Articular Cartilage

Background: Previous studies have shown that Galectin-3, a member of lectin family, is expressed in developing cartilage in mouse embryo and also in growth plate of long bones.   Objective: In the present work, the expression pattern of Galectin-3 in normal and various grades of osteoarthritic (OA) human articular cartilage has been studied.   Methods: Using immunohistochemistry and standard we...